Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185293 | 0.80 | TRPA1 (0.40) | — | |
| SCHEMBL9701765 | 0.77 | TRPA1 (0.30) | — | |
| SCHEMBL5871994 | 0.77 | MME (0.37) | — | |
| SCHEMBL9602863 | 0.77 | CYP3A4 (0.40) | — | |
| SCHEMBL5871216 | 0.74 | PPARA (0.40) | — | |
| SCHEMBL5872189 | 0.74 | MEN1 (0.39) | — | |
| SCHEMBL8807198 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL8545986 | 0.73 | CYP2A6 (0.42) | KCNH2 | |
| SCHEMBL7079774 | 0.71 | — | — | |
| SCHEMBL8880541 | 0.69 | ESR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217963-A | Antiischemic, antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5057506-A | Anticonvulsants, antispasmodic and antischemic agents | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4906621-A | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |