Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethylbenzene SCHEMBL10350569 | 0.77 | MEN1 (0.65) | ALDH1A1RAB9AKMT2AMEN1ADORA2A | |
| SCHEMBL10353587 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TDP1RAB9AKMT2AMEN1 | |
| SCHEMBL17844701 | 0.73 | RAB9A (0.79) | ALDH1A1TDP1RAB9AKMT2AMEN1 | |
| SCHEMBL4778269 | 0.73 | POLB (0.65) | ALDH1A1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL175217 | 0.73 | ADORA2A (0.68) | ALDH1A1RAB9AKMT2AMEN1ADORA2A | |
| SCHEMBL10353722 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TDP1RAB9AKMT2AMEN1 | |
| SCHEMBL10665049 | 0.73 | CYP1A2 (0.46) | ALDH1A1TDP1KMT2AMEN1LMNA | |
| SCHEMBL9839292 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TDP1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6559022 | 0.72 | POLB (0.63) | ALDH1A1RAB9AKMT2AMEN1NPC1 | |
| Bromide SCHEMBL27891199 | 0.72 | ADORA2A (0.67) | ALDH1A1RAB9AKMT2AMEN1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214004-B1 | 4-OH-QUINOLINE-CARBOXYLIC-ACID DERIVATIVES SUBSTITUTED IN POSITION 2 BY A DIHYDROXY-SUBSTITUTED GROUP, POSSIBLY ETHERIFIED OR ESTERIFIED, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-31 | — | — | EP | disclosed |