Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.44 |
| ▸ | GABRP | O00591 | 6/20 | 0.44 |
| ▸ | GABRD | O14764 | 6/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.44 |
| ▸ | GABRE | P78334 | 6/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.44 |
| ▸ | CDC7 | O00311 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935704 | 0.88 | CYP1A2 (0.49) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9518746 | 0.84 | CYP4A11 (0.54) | CYP4F2CYP4A11ALDH1A1KDM4EMAPK1 | |
| SCHEMBL7008579 | 0.83 | CYP1A2 (0.47) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL128612 | 0.83 | CYP1A2 (0.47) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL480291 | 0.83 | CYP4F2 (0.52) | CYP4F2CYP4A11CYP1A2GABRA1GABRG2 | |
| Hydrochloric Acid SCHEMBL20357239 | 0.82 | CYP1A2 (0.46) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL744204 | 0.80 | GABRA1 (0.43) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL743703 | 0.79 | CYP1A2 (0.44) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL127699 | 0.79 | CYP1A2 (0.53) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL13813279 | 0.79 | ALDH1A1 (0.44) | CYP4F2CYP4A11GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217963-A | Antiischemic, antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5057506-A | Anticonvulsants, antispasmodic and antischemic agents | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4906621-A | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4898854-A | NERVOUS SYSTEM DISORDERS | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |