Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 9/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14761832 | 0.82 | DRD2 (0.57) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL22071882 | 0.78 | HSD17B10 (0.54) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL14761461 | 0.78 | SMN1; SMN2 (0.56) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL9602156 | 0.77 | CYP2D6 (0.60) | DRD3DRD2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3954077 | 0.77 | HSD17B10 (0.47) | DRD3DRD2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23673763 | 0.75 | CXCR4 (0.49) | DRD3DRD2MEN1KMT2A | |
| SCHEMBL7281937 | 0.73 | SIGMAR1 (0.42) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL22064074 | 0.73 | ITGB3 (0.56) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL22071884 | 0.73 | ITGB3 (0.43) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL15305135 | 0.72 | MEN1 (0.49) | ITGB3ITGA2BGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309544-B1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-10 | — | — | EP | disclosed |
| EP-0309544-A1 | PSYCHOTROPIC BICYCLIC IMIDES. | AMERICAN HOME PROD (US) | 1989-04-05 | — | — | EP | disclosed |
| WO-1988007530-A1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-10-06 | — | — | WO | disclosed |
| US-4748240-A | Psychotropic bicyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |