Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175217 | 0.87 | ADORA2A (0.68) | FFAR2RAB9ANPC1SMN1; SMN2TP53 | |
| Bromide SCHEMBL27891199 | 0.85 | ADORA2A (0.67) | RAB9ANPC1SMN1; SMN2TP53THRB | |
| Trifluoromethylbenzene SCHEMBL10350569 | 0.83 | MEN1 (0.65) | RAB9ANPC1SMN1; SMN2TP53THRB | |
| Chlorobenzene SCHEMBL27628209 | 0.78 | PLA2G4A (0.52) | FFAR2SMN1; SMN2MEN1KMT2ACYP1A2 | |
| Chlorobenzene SCHEMBL27740260 | 0.77 | FFAR2 (0.51) | FFAR2RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL4687548 | 0.77 | FFAR2 (0.74) | FFAR2RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL12630120 | 0.76 | ACP1 (0.58) | FFAR2RAB9ANPC1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL29855979 | 0.75 | FFAR2 (0.72) | FFAR2RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2683107 | 0.75 | NPC1 (0.76) | FFAR2RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7470030 | 0.74 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214004-B1 | 4-OH-QUINOLINE-CARBOXYLIC-ACID DERIVATIVES SUBSTITUTED IN POSITION 2 BY A DIHYDROXY-SUBSTITUTED GROUP, POSSIBLY ETHERIFIED OR ESTERIFIED, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-31 | — | — | EP | disclosed |
| EP-0214004-A2 | 4-OH-quinoline-carboxylic-acid derivatives substituted in position 2 by a dihydroxy-substituted group, possibly etherified or esterified, process and intermediates for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1987-03-11 | — | — | EP | disclosed |