Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 4/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | IL6 | P05231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835391 | 0.91 | CYP3A4 (0.72) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL9602408 | 0.91 | CYP3A4 (0.72) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL11413837 | 0.87 | CYP3A4 (0.44) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL7610377 | 0.87 | CYP3A4 (0.65) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL29008810 | 0.85 | NR3C1 (0.69) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL11815304 | 0.85 | CYP3A4 (0.63) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL11815312 | 0.85 | CYP3A4 (0.63) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL5187427 | 0.85 | PGR (0.73) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| SCHEMBL5187430 | 0.85 | PGR (0.73) | PGRNR3C1CYP3A4HIF1AABCB11 | |
| Fluprednisolone SCHEMBL19327107 | 0.84 | PGR (0.81) | PGRNR3C1CYP3A4HIF1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374185-B1 | IMPROVED 9$g(a)-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1993-02-10 | — | — | EP | claimed |