Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647309 | 0.78 | LMNA (0.33) | LMNASLC6A2SLC6A4BLMSLC6A3 | |
| SCHEMBL1326815 | 0.76 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL677452 | 0.76 | LMNA (0.32) | LMNATSHR | |
| SCHEMBL2874883 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL6533556 | 0.70 | — | — | |
| SCHEMBL9279330 | 0.70 | — | — | |
| SCHEMBL7480073 | 0.70 | LMNA (0.32) | LMNA | |
| SCHEMBL10901017 | 0.70 | LMNA (0.32) | LMNAMEN1KMT2A | |
| SCHEMBL8651722 | 0.67 | — | — | |
| SCHEMBL4076160 | 0.67 | SLC6A2 (0.35) | LMNASLC6A2SLC6A4BLMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169359-B2 | Functionalized silicones with polyalkylene oxide side chains | NDSU RESEARCH FOUNDATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-20140221549-A1 | FUNCTIONALIZED SILICONES WITH POLYALKYLENE OXIDE SIDE CHAINS | NDSU RESEARCH FOUNDATION (US) | 2014-08-07 | — | — | US | disclosed |
| EP-2721109-A2 | FUNCTIONALIZED SILICONES WITH POLYALKYLENE OXIDE SIDE CHAINS | NDSU Research Foundation (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2013052181-A2 | FUNCTIONALIZED SILICONES WITH POLYALKYLENE OXIDE SIDE CHAINS | NDSU RESEARCH FOUNDATION (US) | 2013-04-11 | — | — | WO | disclosed |
| US-5201998-A | Process for sizing paper with anionic hydrophobic sizing agents and cationic retention aids | CIBA-GEIGY CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |