SCHEMBL677452

SCHEMBL677452

C=CC(=O)N(C(O)C=C)C(O)C=C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9602735 0.76 LMNA (0.33) LMNATSHR
SCHEMBL1041496 0.74 TSHR (0.37) LMNAALDH1A1TSHRFGFR4
SCHEMBL1326815 0.74 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
SCHEMBL157071 0.70 TSHR (0.39) LMNAALDH1A1TSHRFGFR4
SCHEMBL8071175 0.70 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL9279330 0.69
SCHEMBL5474705 0.69 ALDH1A1 (0.38) ALDH1A1
SCHEMBL2874883 0.69 ALDH1A1 (0.32) ALDH1A1
SCHEMBL588653 0.69 TSHR (0.37) ALDH1A1TSHR
SCHEMBL15841446 0.68 TSHR (0.38) LMNAALDH1A1TSHRFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2913365-A1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MeadWestvaco Corporation (US) 2015-09-02 EP claimed
EP-2251379-B1 WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME MEADWESTVACO CORP (US) 2015-01-21 EP claimed
EP-2441804-B1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MEADWESTVACO CORP (US) 2014-12-03 EP claimed
EP-2441804-A1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MeadWestvaco Corporation (US) 2012-04-18 EP claimed
US-7951857-B2 a mixture of bitumen, surfactants, water, aggregate and/or reclaimed asphalts, that is substantially free of volatile solvents; bonding and comprissive strength MEADWESTVACO CORPORATION (US) 2011-05-31 US claimed
EP-1915420-B9 WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME MEADWESTVACO CORP (US) 2011-01-19 EP claimed
EP-2251379-A1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MeadWestvaco Corporation (US) 2010-11-17 EP claimed
WO-2010097524-A1 HYBRID HETEROGENEOUS HYDROGEL AND ITS THERAPEUTIC USE WOERLY STEPHANE (FR) 2010-09-02 WO claimed
EP-1915420-B1 WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME MEADWESTVACO CORP (US) 2010-09-01 EP claimed
US-7731820-B2 Compositions of fluorescent whitening agents CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-06-08 US claimed
US-20080194738-A1 Water-In-Oil Bitumen Dispersion and Methods for Producing Paving Compositions from Same MEADWESTVACO CORPORATION (US) 2008-08-14 US claimed
US-20080073617-A1 Compositions of Fluorescent Whitening Agents CIBA SPECIALTY CHEMICALS CORP. 2008-03-27 US claimed
EP-1805361-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS Ciba Specialty Chemicals Holding Inc. (CH) 2007-07-11 EP claimed
WO-2006045714-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-05-04 WO claimed
EP-1101101-A4 METHOD FOR PRODUCING HYDROPHILIC MONOMERS AND USES THEREOF BIOWHITTAKER MOLUCULAR APPLIC (US) 2005-10-19 EP claimed
US-6464850-B1 CAPILLARY AND MICROCHANNEL ELECTROPHORESIS; HYDROLYTICALLY STABLE,HIGH RESOLUTION; HOMO OR COPOLYMER OF N-(2-HYDROXY ETHYL)ACRYLAMIDE, N-(2-HYDROXYETHYL) METHACRYLAMIDE, N,N-DI(HYDROXYALKYL)ACRYLAMIDE; SUPPRESSES ELECTROENDOOSMOSIS BIOWHITTAKER MOLECULAR APPLICATIONS, INC. 2002-10-15 US claimed
EP-1101101-A1 METHOD FOR PRODUCING HYDROPHILIC MONOMERS AND USES THEREOF Biowhittaker Molucular Applications, Inc. (US) 2001-05-23 EP claimed
WO-2000007002-A1 METHOD FOR PRODUCING HYDROPHILIC MONOMERS AND USES THEREOF BIOWHITTAKER MOLECULAR APPLICATIONS, INC. (US) 2000-02-10 WO claimed
US-4775385-A ACRYLONITRILE BASED ADDITION COPOLYMERS; POLYAMIDE-AMINES; WATER SOLUBLE BENCKISER-KNAPSACK GMBH (DE) 1988-10-04 US claimed
US-4428754-A STABILIZATION OF GHASOHOL THE DOW CHEMICAL COMPANY (US) 1984-01-31 US claimed