Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865991 | 0.90 | CDK4 (0.31) | MAPTSMN1; SMN2 | |
| SCHEMBL9601582 | 0.85 | MAPK14 (0.40) | CYP1A2CYP3A4CYP2D6MEN1MAPT | |
| Fumaric Acid SCHEMBL9603068 | 0.83 | ALDH1A1 (0.34) | LMNAMEN1NPC1MAPTKMT2A | |
| Fumaric Acid SCHEMBL9603065 | 0.83 | ALDH1A1 (0.34) | LMNAMEN1NPC1MAPTKMT2A | |
| SCHEMBL9603188 | 0.83 | MAPT (0.37) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10561829 | 0.81 | MAPT (0.42) | LMNAMAPK1MEN1NPC1MAPT | |
| SCHEMBL9603113 | 0.81 | MAPT (0.37) | LMNAMEN1MAPTKMT2APDE4A | |
| SCHEMBL9601971 | 0.80 | KCNH2 (0.39) | KCNH2CYP1A2CYP2D6HRH3MAPT | |
| Fumaric Acid SCHEMBL9602434 | 0.79 | KMT2A (0.42) | LMNAMEN1MAPTKMT2ASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9602442 | 0.79 | KMT2A (0.42) | LMNAMEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351435-B1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |