Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.46 |
| ▸ | HTR3B | O95264 | 3/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601555 | 0.80 | CHRM3 (0.55) | CHRNA7CHRM3CHRM2CHRM1 | |
| SCHEMBL7265735 | 0.79 | NPC1 (0.61) | CHRNA7CHRM3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7446453 | 0.78 | NPC1 (0.60) | CHRNA7CHRM3CHRM2CHRM1 | |
| SCHEMBL9602968 | 0.77 | CHRM2 (0.50) | CHRNA7CHRM3CHRM2CHRM1HTR3A | |
| SCHEMBL9470813 | 0.77 | CHRM3 (0.51) | CHRNA7CHRM3CHRM2CHRM1 | |
| SCHEMBL6303943 | 0.75 | CHRM3 (0.60) | CHRNA7CHRM3CHRM2CHRM1 | |
| SCHEMBL6304740 | 0.75 | CHRM3 (0.60) | CHRNA7CHRM3CHRM2CHRM1 | |
| SCHEMBL6306861 | 0.75 | CHRM3 (0.60) | CHRNA7CHRM3CHRM2CHRM1 | |
| SCHEMBL9602248 | 0.74 | MEN1 (0.43) | HTR3A | |
| SCHEMBL27822313 | 0.74 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |