Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266703 | 0.81 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRNA7 | |
| Hydrochloric Acid SCHEMBL7439036 | 0.80 | CHRM2 (0.52) | CHRM2CHRM1CHRM3CHRNA7 | |
| SCHEMBL9602854 | 0.77 | CHRNA7 (0.50) | CHRM2CHRM1CHRM3CHRNA7CHRNB2 | |
| SCHEMBL9602391 | 0.76 | MEN1 (0.42) | — | |
| SCHEMBL1956626 | 0.68 | CHRNA7 (0.71) | CHRM2CHRM1CHRM3CHRNA7CHRNB2 | |
| SCHEMBL1082093 | 0.68 | CHRNA7 (0.71) | CHRM2CHRM1CHRM3CHRNA7CHRNB2 | |
| SCHEMBL6564238 | 0.68 | CHRNA7 (0.71) | CHRM2CHRM1CHRM3CHRNA7CHRNB2 | |
| SCHEMBL29604517 | 0.68 | CHRNA7 (0.71) | CHRM2CHRM1CHRM3CHRNA7CHRNB2 | |
| SCHEMBL9531125 | 0.68 | CHRM2 (0.59) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL2819764 | 0.67 | CHRM2 (1.00) | CHRM2CHRM1CHRM3CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |