Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ricasetron SCHEMBL21715163 | 0.81 | NOTUM (0.52) | NOTUM | |
| Ricasetron SCHEMBL634827 | 0.81 | NOTUM (0.52) | NOTUM | |
| Ricasetron SCHEMBL634826 | 0.81 | NOTUM (0.52) | NOTUM | |
| Ricasetron SCHEMBL20362251 | 0.81 | NOTUM (0.52) | NOTUM | |
| Ricasetron SCHEMBL7445859 | 0.81 | NOTUM (0.51) | NOTUM | |
| SCHEMBL9602248 | 0.77 | MEN1 (0.43) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL9602684 | 0.76 | HTR6 (0.46) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL9602968 | 0.76 | CHRM2 (0.50) | — | |
| SCHEMBL7346340 | 0.74 | TMEM97 (0.48) | — | |
| SCHEMBL9601595 | 0.73 | TMEM97 (0.43) | MEN1KMT2AALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |