Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294007 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL4622349 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL30001304 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL3360269 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL9603268 | 0.84 | ALDH1A1 (0.37) | SMN1; SMN2HSD17B10ALDH1A1TSHRMEN1 | |
| SCHEMBL24964950 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL17715216 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL10207610 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PLA2G2APLA2G5HSD17B10ALDH1A1 | |
| SCHEMBL5074810 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL5074809 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130316926-A1 | METHOD FOR THE MONITORING OF SMOKING CESSATION COMPLIANCE AND RECOVERY, THERAPEUTIC INTERVENTION, AND RISK MANAGEMENT | HEALTH DIAGNOSTIC LABORATORY, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| US-7718437-B2 | Method for analyzing N-terminal protein adducts | ADDUCT ANALYS AB (SE) | 2010-05-18 | — | — | US | disclosed |
| EP-1738177-B1 | METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS | ADDUCT ANALYS AB (SE) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007107008-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF DISORDERS OF FAT METABOLISM AND OBESITY | INNODIA INC. (CA) | 2007-09-27 | — | — | WO | disclosed |
| US-20070190659-A1 | Method for analyzing n-terminal protein adducts | ADDUCT ANALYS AB (SE) | 2007-08-16 | — | — | US | disclosed |