Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.71 |
| ▸ | MMP8 | P22894 | 4/20 | 0.71 |
| ▸ | ECE1 | P42892 | 7/20 | 0.69 |
| ▸ | NMBR | P28336 | 2/20 | 0.65 |
| ▸ | MMP2 | P08253 | 3/20 | 0.64 |
| ▸ | MMP7 | P09237 | 1/20 | 0.64 |
| ▸ | MMP14 | P50281 | 1/20 | 0.64 |
| ▸ | MME | P08473 | 2/20 | 0.63 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.62 |
| ▸ | ANPEP | P15144 | 2/20 | 0.62 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.62 |
| ▸ | IL1RN | P18510 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575453 | 0.93 | MMP2 (0.72) | MMP9MMP8NMBRMMP2MMP7 | |
| SCHEMBL12052771 | 0.90 | NMBR (0.71) | MMP9MMP8ECE1NMBRMME | |
| SCHEMBL12052806 | 0.90 | NMBR (0.71) | MMP9MMP8ECE1NMBRMME | |
| SCHEMBL29404813 | 0.89 | MMP9 (0.64) | MMP9MMP8ECE1NMBRERAP1 | |
| SCHEMBL6431245 | 0.87 | MMP8 (0.75) | MMP9MMP8NMBRMMP2MMP7 | |
| SCHEMBL6431194 | 0.87 | ECE1 (0.79) | MMP9MMP8ECE1MMP2MMP7 | |
| SCHEMBL7275505 | 0.86 | NMBR (0.74) | MMP9MMP8ECE1NMBRMMP2 | |
| SCHEMBL12062839 | 0.85 | NMBR (0.69) | MMP9MMP8ECE1NMBRMMP2 | |
| SCHEMBL12052755 | 0.85 | NMBR (0.69) | MMP9MMP8ECE1NMBRMMP2 | |
| SCHEMBL8098291 | 0.85 | NMBR (0.69) | MMP9MMP8ECE1NMBRMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189178-A | Preventing protein destruction | GALARDY RICHARD E (US) | 1993-02-23 | — | — | US | disclosed |