Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597007 | 0.77 | HASPIN (0.44) | MAPTSMN1; SMN2RAB9ANPC1PDE7A | |
| SCHEMBL8563127 | 0.75 | MEN1 (0.59) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8598894 | 0.73 | MEN1 (0.39) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9603355 | 0.73 | TDP1 (0.49) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8600916 | 0.73 | MEN1 (0.61) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8599537 | 0.72 | KMT2A (0.36) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9443340 | 0.71 | TSHR (0.45) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8595123 | 0.71 | EGFR (0.36) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27446164 | 0.70 | ALDH1A1 (0.41) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8601697 | 0.70 | ALDH1A1 (0.42) | KMT2AMAPTSMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |