Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 2/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504329 | 1.00 | TOP2A (0.34) | TOP2ADUTFKBP1ANFKB1NFKB2 | |
| SCHEMBL190828 | 1.00 | TOP2A (0.34) | TOP2ADUTFKBP1ANFKB1NFKB2 | |
| SCHEMBL3739744 | 0.85 | DUT (0.36) | TOP2ADUTFKBP1A | |
| SCHEMBL3628010 | 0.85 | DUT (0.36) | TOP2ADUTFKBP1A | |
| SCHEMBL15957013 | 0.85 | DUT (0.36) | TOP2ADUTFKBP1A | |
| SCHEMBL14273543 | 0.84 | DUT (0.36) | TOP2ADUTFKBP1A | |
| SCHEMBL2738382 | 0.82 | KLK7 (0.34) | NFKB1NFKB2RELANR1H2KLK7 | |
| SCHEMBL15317919 | 0.81 | SMYD2 (0.40) | HTTKLK7KLK5NAMPTKDM4E | |
| SCHEMBL8595433 | 0.81 | SMYD2 (0.40) | HTTKLK7KLK5NAMPTKDM4E | |
| SCHEMBL15320368 | 0.81 | ALDH1A1 (0.38) | TOP2ADUTFKBP1ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235389-A1 | P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| WO-2024215802-A1 | BENZOFURANYL AND BENZOTHIENYL COMPOUNDS AS P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | PTGFR, PTGIS, PTGIR | TOP2A 2566/4885DUT 1245/4885FKBP1A 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.