Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MB | P02144 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837263 | 0.84 | POLB (0.54) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4983137 | 0.82 | POLB (0.51) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10445580 | 0.82 | POLB (0.48) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29939067 | 0.81 | POLB (0.53) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9582949 | 0.81 | POLB (0.53) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15279552 | 0.80 | POLB (0.49) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2855498 | 0.77 | POLB (0.63) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30780902 | 0.75 | POLB (0.53) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30230771 | 0.74 | POLB (0.63) | POLBPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8205051 | 0.74 | GABRA1 (0.53) | POLBPKMSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183941-A | Aminophenol | CLAIROL INCORPORATED (US) | 1993-02-02 | — | — | US | disclosed |
| US-5073173-A | Oxidative hair dye mixture | CLAIROL INCORPORATED (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0398702-A2 | Dye couplers | Bristol-Myers Squibb Company (US) | 1990-11-22 | — | — | EP | disclosed |