Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19507083 | 0.90 | GABRA1 (0.58) | GABRA1GABRB1LMNATP53HTT | |
| SCHEMBL15958521 | 0.80 | GABRA1 (0.48) | GABRA1GABRB1LMNAGCGR | |
| SCHEMBL13220712 | 0.78 | GABRA1 (0.56) | GABRA1GABRB1LMNATP53HTT | |
| SCHEMBL12295349 | 0.78 | GABRA1 (0.56) | GABRA1GABRB1LMNATP53HTT | |
| SCHEMBL17736308 | 0.76 | GABRA1 (0.54) | GABRA1GABRB1LMNATP53HTT | |
| SCHEMBL450499 | 0.76 | ALDH1A1 (0.53) | LMNATP53HTTALDH1A1TSHR | |
| SCHEMBL19506267 | 0.76 | GABRA1 (0.44) | GABRA1GABRB1 | |
| SCHEMBL6238097 | 0.75 | GABRA1 (0.58) | GABRA1GABRB1LMNATP53HTT | |
| SCHEMBL12767956 | 0.74 | GABRA1 (0.78) | GABRA1GABRB1LMNAHTTALDH1A1 | |
| SCHEMBL17071840 | 0.74 | GABRA1 (0.52) | GABRA1GABRB1LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360829-B1 | DEHYDROBROMINATION OF SUBSTITUTED ALPHA-HALOCUMENE | DOWELANCO (US) | 1993-05-26 | — | — | EP | claimed |
| US-4594467-A | DEHYDROBROMINATING ALPH-BROMO-3,5-DICHLORO CUMENE WITH ALKALI METAL HYDROXIDE IN PRESENCE OF PHASE TRANSFER CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-10 | — | — | US | disclosed |