Sugi Predict

Sugi Predict / Compounds / SCHEMBL9604043

SCHEMBL9604043

SCHEMBL9604043

Cc1cc(C)c(-c2cccc3nc(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)oc23)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.45
▸ NPC1 O15118 8/20 0.41
▸ RAB9A P51151 7/20 0.41
▸ KDM4E B2RXH2 5/20 0.39
▸ HPGD P15428 5/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ MAPT P10636 3/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ USP2 O75604 2/20 0.39
▸ CASP3 P42574 2/20 0.39
▸ SENP8 Q96LD8 2/20 0.39
▸ SENP7 Q9BQF6 2/20 0.39
▸ SENP6 Q9GZR1 2/20 0.39
▸ HCRTR1 O43613 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ CETP P11597 1/20 0.39
▸ ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604044 0.88 NPC1 (0.52) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604018 0.86 ALOX5 (0.48) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604034 0.84 ALOX5 (0.51) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604033 0.84 ALOX5 (0.52) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604035 0.83 DHODH (0.53) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604039 0.83 ALOX5 (0.48) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL8281448 0.83 ALOX5 (0.48) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604038 0.82 ALOX5 (0.49) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604022 0.81 ALOX5 (0.49) ALOX5NPC1RAB9AKDM4EHPGD
SCHEMBL9604036 0.81 ALOX5 (0.52) ALOX5NPC1RAB9AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 ALOX5 720/4885NPC1 4611/4885RAB9A 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.