Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465075 | 0.89 | CYP2D6 (0.56) | CYP2D6ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL9873658 | 0.71 | CYP2D6 (0.54) | CYP2D6ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL9868719 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL9414994 | 0.62 | KDM4E (0.41) | CYP2D6ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL11604852 | 0.60 | SIGMAR1 (0.58) | KDM4ESMN1; SMN2GAAKMT2AMEN1 | |
| Anthraquinone SCHEMBL1901249 | 0.60 | MEN1 (1.00) | CYP2D6ALDH1A1KDM4ESMN1; SMN2CASP3 | |
| Anthraquinone SCHEMBL14943 | 0.60 | MEN1 (1.00) | CYP2D6ALDH1A1KDM4ESMN1; SMN2CASP3 | |
| Anthraquinone SCHEMBL29358690 | 0.60 | MEN1 (1.00) | CYP2D6ALDH1A1KDM4ESMN1; SMN2CASP3 | |
| SCHEMBL2493946 | 0.59 | DNMT1 (0.62) | KMT2AMEN1DNMT1 | |
| SCHEMBL9159989 | 0.59 | NPC1 (0.45) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205879-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL 2-(4,4-DISUBSTITUTED 5-OXO-2-IMIDAZOLIN-2-YL)BENZOIC, NICOTINIC AND QUINOLINE-3-CARBOXYLIC ACIDS, ESTERS AND SALTS | AMERICAN CYANAMID COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0205879-A2 | Process for the preparation of herbicidal 2-(4,4-disubstituted 5-oxo-2-imidazolin-2-yl)benzoic, nicotinic and quinoline-3-carboxylic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| EP-0204209-A2 | Imidazo-isoquinoline triones, process for their preparation and agents with a herbicidal activity containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-12-10 | — | — | EP | disclosed |