⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95987 | 0.78 | ALDH1A1 (0.70) | — | |
| SCHEMBL2777431 | 0.77 | — | — | |
| SCHEMBL777671 | 0.75 | ALDH1A1 (0.67) | — | |
| SCHEMBL776647 | 0.75 | ALDH1A1 (1.00) | — | |
| SCHEMBL95856 | 0.74 | ALDH1A1 (0.64) | — | |
| SCHEMBL12110783 | 0.73 | ALDH1A1 (0.63) | — | |
| SCHEMBL96806 | 0.72 | ALDH1A1 (0.61) | — | |
| SCHEMBL15279305 | 0.72 | ALDH1A1 (0.70) | — | |
| SCHEMBL10789238 | 0.71 | PSIP1 (0.52) | — | |
| SCHEMBL95505 | 0.71 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | claimed |
| US-7348339-B2 | 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent | GLAXO GROUP LIMITED (GB) | 2008-03-25 | — | — | US | claimed |
| US-20050197328-A1 | Imidazopyridine derivatives as kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-09-08 | — | — | US | claimed |
| EP-1490367-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-29 | — | — | EP | claimed |
| WO-2003080610-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |
| US-6566547-B1 | 3-alkoxy-2-phenylacrylic acid derivatives | ZENECA LIMITED (GB) | 2003-05-20 | — | — | US | claimed |
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | claimed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | claimed |
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| EP-2845853-B1 | METHOD FOR PRODUCING 1H-TETRAZOLE DERIVATIVE | NIPPON SODA CO (JP) | 2017-01-25 | — | — | EP | disclosed |
| EP-2826773-B1 | COMPOUND, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PURIFYING COMPOUND | NIPPON SODA CO (JP) | 2016-11-02 | — | — | EP | disclosed |
| EP-2407461-B1 | PROCESS FOR PREPARATION OF 1-ALKYL-5-BENZOYL-1H-TETRAZOLE DERIVATIVES | NIPPON SODA CO (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-9233984-B2 | Compound, method for producing compound, and method for purifying compound | NIPPON SODA CO., LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-4822811-A | Carbazole lipoxygenase inhibiting compounds, compositions and use | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |
| US-4822809-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| US-4769387-A | Dibenzofuran lipoxygenase inhibiting compounds, compositions and use | ABBOTT LABORATORIES (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0279263-A2 | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |