Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596480 | 0.88 | THRB (0.36) | THRBLMNACHRM2CHRM5CHRM1 | |
| SCHEMBL22334802 | 0.78 | CHRM2 (0.33) | THRBLMNACHRM2CHRM5CHRM1 | |
| SCHEMBL13561266 | 0.78 | CHRM2 (0.33) | THRBLMNACHRM2CHRM5CHRM1 | |
| SCHEMBL18802700 | 0.77 | THRB (0.42) | THRBLMNACHRM2CHRM5CHRM1 | |
| SCHEMBL22837183 | 0.77 | THRB (0.42) | THRBLMNACHRM2CHRM5CHRM1 | |
| SCHEMBL29957418 | 0.76 | CHRM2 (0.36) | LMNACHRM2CHRM5CHRM1TSHR | |
| SCHEMBL8283547 | 0.74 | THRB (0.44) | THRBLMNA | |
| SCHEMBL23261024 | 0.72 | CHRM2 (0.34) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| SCHEMBL23261025 | 0.72 | CHRM2 (0.34) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| SCHEMBL25141269 | 0.72 | CHRM5 (0.33) | CHRM2CHRM5CHRM1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | KHK, HKDC1, HK2 | THRB 4404/4885LMNA 4298/4885CHRM2 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.