Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.84 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.84 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.76 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.74 |
| ▸ | NT5E | P21589 | 4/20 | 0.73 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.73 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.73 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.73 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.65 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13033868 | 1.00 | P2RX3 (0.84) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL9607775 | 1.00 | P2RX3 (0.84) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL21058279 | 0.95 | P2RX3 (0.76) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL9607782 | 0.92 | P2RX3 (0.98) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL30076630 | 0.92 | P2RX3 (0.98) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL29941330 | 0.92 | P2RX3 (0.98) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL4319955 | 0.92 | P2RX3 (0.98) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL13033867 | 0.92 | P2RX3 (0.98) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL14178287 | 0.91 | P2RX3 (1.00) | P2RX3P2RX2P2RX4DNPH1NT5E | |
| SCHEMBL15794372 | 0.91 | P2RX3 (1.00) | P2RX3P2RX2P2RX4DNPH1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, WRN, ADAR | P2RX3 757/4885P2RX2 763/4885P2RX4 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.