Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599143 | 0.80 | PIN1 (0.42) | MMP2KDM4EGAASMN1; SMN2 | |
| SCHEMBL7424608 | 0.80 | MMP2 (0.61) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL20630811 | 0.79 | MMP2 (0.60) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL4605593 | 0.79 | MMP2 (0.60) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL28296067 | 0.78 | MMP2 (0.58) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL14744177 | 0.78 | MMP2 (0.67) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL8653203 | 0.78 | MMP2 (0.67) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL31373939 | 0.78 | MMP2 (0.58) | MMP2MAPK1CYP1A2KDM4EGLA | |
| Hydrochloric Acid SCHEMBL14744176 | 0.76 | MMP2 (0.65) | MMP2MAPK1CYP1A2KDM4EGLA | |
| SCHEMBL28296065 | 0.75 | MMP2 (0.56) | MMP2MAPK1CYP1A2KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180837-A | PILOSININE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-01-19 | — | — | US | disclosed |