SCHEMBL9605928

SCHEMBL9605928

CNNc1ccc(C(=O)O)cn1

nearest known ligand 0.73

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 18/20 0.73
HCAR2 Q8TDS4 2/20 0.57
P4HA1 P13674 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
NNMT P40261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185895 0.85 HCAR3 (1.00) HCAR3HCAR2P4HA1P4HTMNNMT
SCHEMBL30403146 0.85 HCAR3 (1.00) HCAR3HCAR2P4HA1P4HTMNNMT
Hydrochloric Acid SCHEMBL6474495 0.83 HCAR3 (0.96) HCAR3HCAR2P4HA1P4HTMNNMT
Hydrochloric Acid SCHEMBL4035906 0.83 HCAR3 (0.96) HCAR3HCAR2P4HA1P4HTMNNMT
SCHEMBL14167607 0.81 HCAR3 (0.62) HCAR3HCAR2P4HA1P4HTM
SCHEMBL14341697 0.80 HCAR3 (0.76) HCAR3HCAR2P4HA1P4HTM
SCHEMBL27874609 0.79 HCAR3 (0.69) HCAR3HCAR2
SCHEMBL3566055 0.79 HCAR3 (0.69) HCAR3HCAR2P4HA1P4HTM
SCHEMBL82675 0.78 HCAR3 (0.68) HCAR3HCAR2
SCHEMBL158601 0.77 HCAR3 (0.67) HCAR3HCAR2P4HA1P4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183587-A1 COMPOUNDS AND USES THEREOF YUMANITY THERAPEUTICS, INC. (US) 2019-09-26 WO disclosed
EP-2295407-B1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INC (US) 2014-11-05 EP disclosed
WO-2012069608-A1 TECHNETIUM-99M COMPLEX AS A TOOL FOR THE IN VIVO DIAGNOSIS OF CANCEROUS TUMOURS PIERRE FABRE MEDICAMENT (FR) 2012-05-31 WO disclosed