SCHEMBL158601

SCHEMBL158601

NNc1ccc(C(=O)O)cn1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 17/20 0.67
GABRP O00591 1/20 0.57
GABRD O14764 1/20 0.57
GABRA1 P14867 1/20 0.57
GABRB1 P18505 1/20 0.57
GABRG2 P18507 1/20 0.57
GABRB3 P28472 1/20 0.57
GABRA5 P31644 1/20 0.57
GABRA3 P34903 1/20 0.57
GABRA2 P47869 1/20 0.57
GABRB2 P47870 1/20 0.57
GABRA4 P48169 1/20 0.57
GABRE P78334 1/20 0.57
GABRA6 Q16445 1/20 0.57
GABRG1 Q8N1C3 1/20 0.57
GABRG3 Q99928 1/20 0.57
GABRQ Q9UN88 1/20 0.57
HCAR2 Q8TDS4 2/20 0.56
P4HA1 P13674 2/20 0.55
P4HTM Q9NXG6 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505896 1.00 HCAR3 (0.67) HCAR3GABRPGABRDGABRA1GABRB1
Ammonia Solution, Strong SCHEMBL28249483 0.98 HCAR3 (0.65) HCAR3GABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL5789616 0.98 HCAR3 (0.65) HCAR3GABRPGABRDGABRA1GABRB1
Acetone SCHEMBL7024428 0.94 HCAR3 (0.66) HCAR3GABRPGABRDGABRA1GABRB1
Succinic Acid SCHEMBL23070477 0.91 HCAR3 (0.57) HCAR3GABRPGABRDGABRA1GABRB1
Succinimide SCHEMBL28163974 0.87 HCAR3 (0.53) HCAR3GABRPGABRDGABRA1GABRB1
Succinimide SCHEMBL25397856 0.86 HCAR3 (0.51) HCAR3GABRPGABRDGABRA1GABRB1
Benzaldehyde SCHEMBL27567924 0.86 HCAR3 (0.55) HCAR3GABRPGABRDGABRA1GABRB1
SCHEMBL8722229 0.84 NNMT (0.50) HCAR3HCAR2
SCHEMBL383413 0.84 NNMT (0.70) HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036881-A Somatostatin receptor-targeting compounds and uses thereof 无锡诺宇医药科技有限公司 2026-05-15 CN claimed
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS NORROY BIOSCIENCE CO LTD (CN) 2026-05-14 US claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20260061085-A1 CYCLIC PEPTIDE AND PREPARATION METHOD THEREFOR, AND COMPLEX COMPRISING SAME AND USE THEREOF HEXIN SUZHOU PHARMACEUTICAL TECH CO LTD (CN) 2026-03-05 US claimed
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 US claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
EP-4612144-A1 CARBONIC ANHYDRASE IX LIGANDS FOR TARGETED DELIVERY APPLICATIONS Philochem AG (CH) 2025-09-10 EP claimed
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 US claimed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 EP claimed
EP-4587062-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA Cellis AG (CH) 2025-07-23 EP claimed
EP-1846042-A2 CONJUGATES FOR DUAL IMAGING AND RADIOCHEMOTHERAPY: COMPOSITION, MANUFACTURING, AND APPLICATIONS Board of Regents, The University of Texas System (US) 2007-10-24 EP claimed
US-20070196275-A1 Diagnostic Imaging Compositions, Their Methods Of Synthesis And Use NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-08-23 US claimed
EP-1784422-A2 GLP-1 AND EXENDIN RELATED INVENTION Philipps-Universität Marburg (DE) 2007-05-16 EP claimed
US-20060182687-A1 Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2006-08-17 US claimed
WO-2006074272-A2 CONJUGATES FOR DUAL IMAGING AND RADIOCHEMOTHERAPY: COMPOSITION, MANUFACTURING, AND APPLICATIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-07-13 WO claimed
WO-2006024275-A2 GLP-1 AND EXENDIN RELATED INVENTION PHILIPPS-UNIVERSITÄT MARBURG (DE) 2006-03-09 WO claimed
EP-1389090-A2 DIAGNOSTIC IMAGING COMPOSITIONS, THEIR METHODS OF SYNTHESIS AND USE Board of Regents, The University of Texas System (US) 2004-02-18 EP claimed
US-20030003048-A1 Diagnostic imaging compositions, their methods of synthesis and use NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-02 US claimed
WO-2002087498-A2 DIAGNOSTIC IMAGING COMPOSITIONS, THEIR METHODS OF SYNTHESIS AND USE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2002-11-07 WO claimed
EP-0384769-B1 Protein labelling JOHNSON MATTHEY PLC (GB) 1996-04-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061085-A1 CYCLIC PEPTIDE AND PREPARATION METHOD THEREFOR, AND COMPLEX COMPRISING SAME AND USE THEREOF ANPEP, XPNPEP1, SLC7A1 HCAR3 1880/4885GABRP 1269/4885GABRD 1557/4885
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS CA9, CA11, CA12 HCAR3 140/4885GABRP 534/4885GABRD 1238/4885
US-20060182687-A1 Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications CCNY, B3GAT3, FUT5 HCAR3 689/4885GABRP 4198/4885GABRD 4390/4885
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CD47, TFRC, L1CAM HCAR3 3729/4885GABRP 1703/4885GABRD 2748/4885
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP HCAR3 3917/4885GABRP 3542/4885GABRD 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.