Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 18/20 | 1.00 |
| ▸ | NNMT | P40261 | 1/20 | 0.70 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.60 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185895 | 1.00 | HCAR3 (1.00) | HCAR3NNMTHCAR2P4HA1P4HTM | |
| Hydrochloric Acid SCHEMBL4035906 | 0.98 | HCAR3 (0.96) | HCAR3NNMTHCAR2P4HA1P4HTM | |
| Hydrochloric Acid SCHEMBL6474495 | 0.98 | HCAR3 (0.96) | HCAR3NNMTHCAR2P4HA1P4HTM | |
| 6-Chloronicotinic Acid SCHEMBL4044448 | 0.88 | HCAR3 (0.78) | HCAR3NNMTHCAR2 | |
| SCHEMBL9605928 | 0.85 | HCAR3 (0.73) | HCAR3NNMTHCAR2P4HA1P4HTM | |
| SCHEMBL12588541 | 0.84 | HCAR3 (0.72) | HCAR3NNMTHCAR2 | |
| SCHEMBL14341697 | 0.83 | HCAR3 (0.76) | HCAR3HCAR2P4HA1P4HTM | |
| SCHEMBL18715411 | 0.82 | HCAR3 (0.70) | HCAR3NNMT | |
| SCHEMBL4320704 | 0.82 | NNMT (1.00) | HCAR3NNMT | |
| SCHEMBL27874609 | 0.82 | HCAR3 (0.69) | HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-107108534-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-09 | — | — | CN | disclosed |