Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 7/20 | 0.48 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608121 | 0.86 | RAB9A (0.44) | TNFRAB9ANOD1FDPSHTT | |
| SCHEMBL9608113 | 0.85 | EGFR (0.43) | TNFRAB9ANOD1FDPSEGFR | |
| SCHEMBL9608097 | 0.83 | RAB9A (0.52) | TNFRAB9ANOD1FDPSLMNA | |
| SCHEMBL9608119 | 0.83 | RAB9A (0.41) | TNFRAB9ANOD1FDPSLMNA | |
| SCHEMBL9608124 | 0.83 | RAB9A (0.41) | PIP4K2ATNFRAB9ANOD1FDPS | |
| SCHEMBL9608103 | 0.81 | TNF (0.48) | PIP4K2APIP4K2CTNFRAB9ANOD1 | |
| SCHEMBL9608116 | 0.80 | RAB9A (0.44) | TNFRAB9ANOD1FDPSLMNA | |
| SCHEMBL9608126 | 0.78 | RAB9A (0.46) | TNFRAB9ANOD1FDPSLMNA | |
| SCHEMBL9608111 | 0.78 | RAB9A (0.42) | TNFRAB9ANOD1FDPSLMNA | |
| SCHEMBL8491209 | 0.78 | RAB9A (0.50) | TNFRAB9ANOD1FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-8586505-B2 | 4-(3-butynyl)aminopyrimidine derivatives as pest control agents for agricultural and horticultural use | SDS BIOTECH K. K. (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | SDS BIOTECH K.K. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | SDS BIOTECH K.K. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | SDS BIOTECH K.K. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | HCN1, HCN2, HCN3 | PIP4K2A 2396/4885PIP4K2C 2187/4885TNF 4828/4885 |
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | CBR3, CBR1, HRH2 | PIP4K2A 1504/4885PIP4K2C 1259/4885TNF 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.