Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419966 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1CASP6CTSBCDK2 | |
| SCHEMBL15801194 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TDP1CASP6GPR35TSHR | |
| SCHEMBL9608371 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1CASP6CTSBCDK2 | |
| SCHEMBL9608361 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TDP1CASP6CDK2GPR35 | |
| SCHEMBL14867804 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TDP1CASP6CTSBCDK2 | |
| SCHEMBL14859939 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TDP1CASP6CTSBCDK2 | |
| SCHEMBL9608369 | 0.78 | FBP1 (0.47) | ALDH1A1TDP1CASP6CDK2TSHR | |
| SCHEMBL9735773 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TDP1CASP6GPR35TSHR | |
| SCHEMBL13206983 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1CASP6CTSBCDK2 | |
| SCHEMBL13198027 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1CASP6CTSBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160122813-A1 | Methods And Kits Using Extended Rhodamine Dyes | THE PERKIN-ELMER CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-9309561-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140171336-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2014-06-19 | — | — | US | disclosed |
| US-8628975-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20120135885-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2012-05-31 | — | — | US | disclosed |
| US-8124746-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053282-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2011-03-03 | — | — | US | disclosed |