SCHEMBL9608425

SCHEMBL9608425

COC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3c(C)cc(OC)cc3O)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
NPSR1 Q6W5P4 2/20 0.51
POLB P06746 1/20 0.51
KDM4A O75164 1/20 0.50
HPGD P15428 3/20 0.44
ALDH1A1 P00352 2/20 0.44
GAA P10253 2/20 0.44
EGFR P00533 1/20 0.44
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
VDR P11473 2/20 0.40
IDO1 P14902 1/20 0.40
ESR1 P03372 1/20 0.40
THRA P10827 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608445 0.90 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9609238 0.89 KMT2A (0.48) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608424 0.89 MAPT (0.53) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL17917578 0.88 MEN1 (0.47) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9609244 0.87 MEN1 (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608422 0.85 MAPT (0.53) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608460 0.85 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL15910001 0.84 MAPT (0.60) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608388 0.84 MAPT (0.60) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608419 0.83 MEN1 (0.53) MAPTMEN1KMT2ANPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885MEN1 2282/4885KMT2A 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.