SCHEMBL9608451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12228462	0.94	KMT2A (0.55)	TDP1MEN1KMT2AMAPTPOLB
	SCHEMBL9608454	0.86	MAPT (0.57)	MEN1KMT2AMAPTPOLBNPSR1
	SCHEMBL9608388	0.85	MAPT (0.60)	TDP1MEN1KMT2AMAPTPOLB
	SCHEMBL15910001	0.85	MAPT (0.60)	TDP1MEN1KMT2AMAPTPOLB
	SCHEMBL9608456	0.83	MAPT (0.54)	TDP1MEN1KMT2AMAPTPOLB
	SCHEMBL9608450	0.83	MAPT (0.57)	TDP1MEN1KMT2AMAPTPOLB
	SCHEMBL9608462	0.83	MAPT (0.56)	TDP1MEN1KMT2AMAPTPOLB
	SCHEMBL9608434	0.82	MAPT (0.58)	MEN1KMT2AMAPTPOLBNPSR1
	SCHEMBL12228440	0.82	EGFR (0.59)	MEN1KMT2AMAPTPOLBNPSR1
	SCHEMBL9608419	0.82	MEN1 (0.53)	MEN1KMT2AMAPTPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.