SCHEMBL9608529

SCHEMBL9608529

COC(=O)c1cccc(-c2nc(-c3ccccc3O)nc(-c3cc(NC(C)=O)ccc3O)n2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
MAPT P10636 6/20 0.52
ALDH1A1 P00352 4/20 0.52
NPSR1 Q6W5P4 3/20 0.52
HPGD P15428 3/20 0.52
GAA P10253 1/20 0.52
POLB P06746 1/20 0.48
RAB9A P51151 5/20 0.46
NPC1 O15118 3/20 0.46
KDM4E B2RXH2 2/20 0.45
ADORA2A P29274 2/20 0.45
PLAU P00749 2/20 0.44
KDM5A P29375 1/20 0.44
KDM4D Q6B0I6 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
KDM5B Q9UGL1 1/20 0.44
KDM3A Q9Y4C1 1/20 0.44
ERN1 O75460 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608487 0.88 MEN1 (0.60) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608540 0.86 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608545 0.84 MEN1 (0.55) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608537 0.84 MEN1 (0.57) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608536 0.84 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608415 0.84 MAPT (0.56) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608543 0.83 MEN1 (0.56) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608531 0.81 KMT2A (0.56) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608539 0.81 MEN1 (0.49) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL9608530 0.80 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MEN1 2282/4885KMT2A 1270/4885MAPT 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.