Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16658709 | 0.78 | MTNR1A (0.45) | SMN1; SMN2NPC1RAB9ANAMPTKDM4E | |
| SCHEMBL8533416 | 0.76 | GPR52 (0.48) | SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL16658707 | 0.74 | TRPV1 (0.45) | SMN1; SMN2KDM4EEPHX1 | |
| SCHEMBL16658716 | 0.73 | TRPV1 (0.47) | KDM4EEPHX1 | |
| SCHEMBL16658729 | 0.73 | TRPV1 (0.47) | KDM4EEPHX1 | |
| SCHEMBL17391736 | 0.72 | TSHR (0.54) | SMN1; SMN2RECQLLMNAIDO1 | |
| SCHEMBL24095771 | 0.72 | NPC1 (0.54) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL15534342 | 0.71 | GPR52 (0.50) | — | |
| Hydrochloric Acid SCHEMBL21571422 | 0.71 | IDO1 (0.54) | SMN1; SMN2RECQLLMNAIDO1 | |
| SCHEMBL15534344 | 0.71 | GPR52 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |