Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608852 | 0.88 | SIGMAR1 (0.46) | GPR52 | |
| SCHEMBL16658711 | 0.86 | GPR52 (0.47) | GPR52ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL15534342 | 0.86 | GPR52 (0.50) | GPR52MAPTHTT | |
| SCHEMBL15534344 | 0.86 | GPR52 (0.50) | GPR52MAPTHTT | |
| SCHEMBL16658709 | 0.78 | MTNR1A (0.45) | NPC1RAB9AGAATAAR1ALDH1A1 | |
| SCHEMBL9608859 | 0.77 | ATM (0.48) | GPR52TAAR1MAPT | |
| SCHEMBL16658707 | 0.77 | TRPV1 (0.45) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9608840 | 0.76 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8536844 | 0.76 | MEN1 (0.47) | GPR52TAAR1MAPT | |
| Hydrochloric Acid SCHEMBL8536840 | 0.76 | MEN1 (0.47) | GPR52TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |