Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279272 | 0.91 | CYP19A1 (0.39) | MEN1KMT2AMGLLCYP19A1CYP11B2 | |
| SCHEMBL9608744 | 0.89 | TP53 (0.38) | MEN1KMT2APTGS2 | |
| SCHEMBL14448448 | 0.80 | TDP1 (0.44) | MEN1KMT2ACYP19A1CYP11B2PTGS2 | |
| SCHEMBL279561 | 0.79 | PTGS2 (0.41) | MEN1KMT2APTGS2ESR1CYP2D6 | |
| SCHEMBL12533728 | 0.74 | PTGS2 (0.45) | KMT2ACYP19A1CYP11B2PTGS2ESR1 | |
| SCHEMBL278974 | 0.74 | CYP19A1 (0.46) | MEN1KMT2ACYP19A1CYP11B2PTGS2 | |
| SCHEMBL279157 | 0.74 | CYP19A1 (0.36) | CYP19A1CYP11B2PTGS2ESR1CYP2D6 | |
| SCHEMBL278983 | 0.74 | CYP19A1 (0.36) | KMT2ACYP19A1CYP11B2PTGS2ESR1 | |
| SCHEMBL9608862 | 0.74 | CYP19A1 (0.36) | CYP19A1CYP11B2PTGS2ESR1CYP2D6 | |
| SCHEMBL12533733 | 0.73 | STAT3 (0.41) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273517-B2 | Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge | FUJI XEROX CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120134713-A1 | METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE | FUJI XEROX CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |