Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279561 | 0.91 | PTGS2 (0.41) | TP53PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL9608959 | 0.89 | MEN1 (0.36) | PTGS2MEN1KMT2A | |
| SCHEMBL9607505 | 0.81 | TP53 (0.36) | TP53PTGS2THRATHRB | |
| SCHEMBL9098089 | 0.81 | PTGS2 (0.46) | TP53PTGS2CYP4A11MEN1KMT2A | |
| SCHEMBL13313028 | 0.80 | PTGS2 (0.36) | TP53PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL279256 | 0.80 | PTGS2 (0.36) | TP53PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL279272 | 0.80 | CYP19A1 (0.39) | PTGS2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14950688 | 0.75 | PTGS2 (0.48) | TP53PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL12572204 | 0.75 | PTGS2 (0.48) | TP53PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL13337948 | 0.75 | SMN1; SMN2 (0.43) | TP53PTGS2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273517-B2 | Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge | FUJI XEROX CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120134713-A1 | METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE | FUJI XEROX CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |