SCHEMBL9611215

SCHEMBL9611215

C=CC(=O)OCOc1ccc(C(=O)Oc2ccc3c(c2)C(C)(C)c2cc(OC(=O)c4ccc(OCOC(=O)C=C)cc4F)ccc2-3)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.38
MAOB P27338 4/20 0.34
MAOA P21397 1/20 0.33
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 1/20 0.32
LSS P48449 1/20 0.32
PRSS1 P07477 1/20 0.32
TMPRSS15 P98073 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
PARP10 Q53GL7 2/20 0.31
PARP14 Q460N5 1/20 0.31
PARP15 Q460N3 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15480718 0.95 THRB (0.39) HIF1AMAOBKMT2AMEN1LSS
SCHEMBL13226626 0.92 MAOB (0.35) HIF1AMAOBMAOAPARP10PARP15
SCHEMBL11986091 0.92 HIF1A (0.38) HIF1APOLBMAPTKMT2APRSS1
SCHEMBL14185455 0.90 HIF1A (0.35) HIF1AMAOBMAOAPOLBMAPT
SCHEMBL12769578 0.89 RARA (0.33) MAPTKMT2AMEN1
SCHEMBL10061461 0.88 LSS (0.39) HIF1AKMT2AMEN1LSSALDH1A1
SCHEMBL12154248 0.86 MAOB (0.39) MAOBMAOAKMT2APARP10PARP15
SCHEMBL11986088 0.86 HIF1A (0.38) HIF1AMAOBMAOAPOLBMAPT
SCHEMBL14117058 0.85 NPC1 (0.34) KMT2AMEN1
SCHEMBL13226597 0.85 HIF1A (0.36) HIF1APOLBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9541690-B2 Film using polymerizable liquid crystal composition containing peeling preventive agent JNC CORPORATION (JP) 2017-01-10 US disclosed
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-9399736-B2 Optically anisotropic substance and liquid crystal display JNC CORPORATION (JP) 2016-07-26 US disclosed
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-20150361345-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-12-17 US disclosed
US-9080100-B2 Polymerizable liquid crystal composition JNC CORPORATION (JP) 2015-07-14 US disclosed
US-20150177567-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-06-25 US disclosed
US-20150146156-A1 OPTICALLY ANISOTROPIC SUBSTANCE AND LIQUID CRYSTAL DISPLAY JNC CORPORATION (JP) 2015-05-28 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed
US-7527746-B2 Liquid crystal polyfunctional acrylate derivative and polymer thereof CHISSO CORPORATION (JP) 2009-05-05 US disclosed
US-7488519-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-02-10 US disclosed
US-7476423-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-01-13 US disclosed
US-20080241431-A1 Polymerizable liquid crystal composition CHISSO CORPORATION 2008-10-02 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-20080152844-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-06-26 US disclosed
US-7378135-B2 Polymerizable liquid crystal composition and optically anisotropic thin film CHISSO CORPORATION (JP) 2008-05-27 US disclosed
US-20080014374-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-01-17 US disclosed
US-20080003381-A1 Overcoat film composition, color filter substrate, and liquid crystal display element CHISSO CORPORATION 2008-01-03 US disclosed