Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117058 | 0.96 | NPC1 (0.34) | RARARARBKMT2AMEN1NPC1 | |
| SCHEMBL12769568 | 0.96 | NPC1 (0.34) | RARARARBKMT2AMEN1NPC1 | |
| SCHEMBL14117094 | 0.95 | PDK2 (0.36) | KMT2AMEN1NPC1CASP3SENP8 | |
| SCHEMBL9611215 | 0.89 | HIF1A (0.38) | KMT2AMEN1MAPT | |
| SCHEMBL13664616 | 0.87 | HIF1A (0.35) | RARARARBKMT2AMEN1THRB | |
| SCHEMBL11986166 | 0.87 | HIF1A (0.36) | RARARARBKMT2AMEN1THRB | |
| SCHEMBL14614873 | 0.86 | L3MBTL1 (0.41) | KMT2AMEN1NPC1CASP3SENP8 | |
| SCHEMBL11986046 | 0.85 | GSTP1 (0.36) | RARARARBKMT2AMEN1NPC1 | |
| SCHEMBL15480718 | 0.84 | THRB (0.39) | RARARARBKMT2AMEN1THRB | |
| SCHEMBL13024945 | 0.84 | THRB (0.39) | RARARARBKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120274888-A1 | OPTICALLY ANISOTROPIC SUBSTANCE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-11-01 | — | — | US | disclosed |
| US-RE42221-E1 | Polymerizable liquid crystal composition and polymer thereof | CHISSO CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-20100297367-A1 | OPTICALLY ANISOTROPIC SUBSTANCE | CHISSO CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7378135-B2 | Polymerizable liquid crystal composition and optically anisotropic thin film | CHISSO CORPORATION (JP) | 2008-05-27 | — | — | US | disclosed |