Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18720002 | 0.79 | TSHR (0.45) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL16826977 | 0.79 | USP2 (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL27251834 | 0.76 | KDM4E (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL17117078 | 0.73 | TSHR (0.35) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL23171105 | 0.73 | LPAR1 (0.42) | USP2ALDH1A1 | |
| SCHEMBL7135483 | 0.72 | TSHR (0.45) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7135487 | 0.72 | TSHR (0.45) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL10798698 | 0.72 | ALDH1A1 (0.43) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL502063 | 0.71 | — | — | |
| SCHEMBL21023385 | 0.70 | USP2 (0.38) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136037-A1 | DEUTERIUM-ENRICHED RUBOXISTAURIN | PROTIA, LLC (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136037-A1 | DEUTERIUM-ENRICHED RUBOXISTAURIN | RDX, HRH3, QDPR | USP2 641/4885TSHR 3323/4885KDM4E 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.