SCHEMBL14947869

SCHEMBL14947869

c1ccc(-n2c(-c3ccc(-c4nc5ncccc5n4-c4ccccc4)cc3)nc3ncccc32)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
BACE1 P56817 1/20 0.55
ALDH1A1 P00352 4/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
GRIA1 P42261 1/20 0.41
CACNG8 Q8WXS5 1/20 0.41
CACNG2 Q9Y698 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
AVPR1A P37288 1/20 0.40
PI4KA P42356 1/20 0.40
PI4K2B Q8TCG2 1/20 0.40
PI4K2A Q9BTU6 1/20 0.40
PI4KB Q9UBF8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10247452 0.97 KMT2A (0.64) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL15747069 0.94 KMT2A (0.54) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL15746020 0.89 ALDH1A1 (0.49) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL19961706 0.88 KMT2A (0.48) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL14947879 0.88 KMT2A (0.54) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL2602373 0.87 KMT2A (0.49) KMT2ABACE1ALDH1A1CYP2C19NPC1
SCHEMBL18875281 0.85 KMT2A (0.48) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL26855425 0.84 ALDH1A1 (0.48) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL13052994 0.84 KMT2A (0.49) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL22141814 0.83 KMT2A (0.44) KMT2ABACE1ALDH1A1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element UDC IRELAND LIMITED (IE) 2023-07-11 US disclosed
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element UDC IRELAND LIMITED (IE) 2023-07-11 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 KMT2A 3861/4885BACE1 892/4885ALDH1A1 203/4885
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element ALDH1A2, AOC2, AOX1 KMT2A 2412/4885BACE1 540/4885ALDH1A1 39/4885
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element L1CAM, ZYX, H1-0 KMT2A 1405/4885BACE1 1543/4885ALDH1A1 326/4885
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 KMT2A 3600/4885BACE1 3308/4885ALDH1A1 981/4885
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element LAS1L, CCNL2, CDC5L KMT2A 2814/4885BACE1 1751/4885ALDH1A1 939/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 KMT2A 3600/4885BACE1 3308/4885ALDH1A1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.