Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609004 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL13259969 | 0.78 | ACE (0.36) | BRD4FKBP1ALTA4HMMP2ANPEP | |
| SCHEMBL13260166 | 0.77 | LTA4H (0.36) | FKBP1ALTA4HMMP2ANPEPPOLB | |
| SCHEMBL3731407 | 0.77 | LTA4H (0.36) | FKBP1ALTA4HMMP2ANPEPPOLB | |
| SCHEMBL8277961 | 0.74 | ACE (0.44) | KMT2ASMN1; SMN2 | |
| SCHEMBL10565798 | 0.74 | POLB (0.38) | FKBP1ALTA4HMMP2ANPEPPOLB | |
| SCHEMBL10564754 | 0.68 | POLB (0.41) | BRD4FKBP1ALTA4HMMP2ANPEP | |
| SCHEMBL25867562 | 0.67 | ALDH1A1 (0.47) | FKBP1AKMT2ASMN1; SMN2 | |
| SCHEMBL10671518 | 0.66 | FKBP1A (0.39) | FKBP1ALTA4HMMP2ANPEPPOLB | |
| SCHEMBL10201316 | 0.66 | FKBP1A (0.41) | BRD4FKBP1ALTA4HMMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |