Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.62 |
| ▸ | CA1 | P00915 | 15/20 | 0.62 |
| ▸ | CA12 | O43570 | 8/20 | 0.62 |
| ▸ | CA9 | Q16790 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632848 | 0.85 | CA2 (0.50) | CA2CA1CA12CA9MAPT | |
| SCHEMBL9353883 | 0.82 | TSHR (0.53) | CA2CA1CA12CA9MAPT | |
| SCHEMBL359584 | 0.82 | CA2 (0.64) | CA2CA1CA12CA9MAPT | |
| SCHEMBL29932745 | 0.80 | CA2 (0.61) | CA2CA1CA12CA9MAPT | |
| Hydrochloric Acid SCHEMBL11777840 | 0.80 | CA2 (0.61) | CA2CA1CA12CA9MAPT | |
| SCHEMBL8349259 | 0.80 | CA2 (0.61) | CA2CA1CA12CA9MAPT | |
| SCHEMBL27747721 | 0.79 | CA1 (0.76) | CA2CA1CA12CA9MAPT | |
| SCHEMBL359383 | 0.79 | CA1 (0.73) | CA2CA1CA12CA9MAPT | |
| SCHEMBL1593097 | 0.78 | CA1 (0.64) | CA2CA1CA12CA9MAPT | |
| SCHEMBL7495027 | 0.78 | CA1 (0.69) | CA2CA1CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137166-B1 | 4, 6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2012-05-30 | — | — | EP | disclosed |