SCHEMBL359584

SCHEMBL359584

NNc1cccc(S(N)(=O)=O)c1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.64
CA1 P00915 12/20 0.64
CA12 O43570 7/20 0.61
CA9 Q16790 7/20 0.61
CA4 P22748 2/20 0.61
CA14 Q9ULX7 2/20 0.61
MAPT P10636 2/20 0.59
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
POLB P06746 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11777840 0.98 CA2 (0.61) CA2CA1CA12CA9CA4
SCHEMBL29932745 0.82 CA2 (0.61) CA2CA1CA12CA9CA4
SCHEMBL8349259 0.82 CA2 (0.61) CA2CA1CA12CA9CA4
SCHEMBL393137 0.82 TSHR (0.62) CA2CA1CA12CA9CA4
SCHEMBL1117957 0.82 ROCK1 (0.51) CA2CA1CA12CA9MAPT
SCHEMBL9612082 0.82 CA2 (0.62) CA2CA1CA12CA9CA4
SCHEMBL13734653 0.80 HTR6 (0.54) CA2CA1CA12CA9MAPT
Sulfuric Acid SCHEMBL27953344 0.80 TSHR (0.60) CA2CA1CA12CA9MAPT
SCHEMBL2398133 0.79 CA2 (1.00) CA2CA1CA12CA9CA4
SCHEMBL7563290 0.79 CA2 (0.57) CA2CA1CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109521136-A The method that derivatization HPLC-DAD method measures benzene hydrazine and its derivative in drug or synthetic intermediate 中国药科大学 2019-03-26 CN claimed
CN-105805426-B Pipeline runs through device 上海火克新材料有限公司 2017-10-27 CN claimed
EP-0382437-B1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-08-16 EP claimed
US-5198566-A N-substituted-3-(substituted hydrazino)-benzenesulfonamides KUREHA KAGAKU KOGYO K.K. (JP) 1993-03-30 US claimed
EP-0382437-A1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP claimed
US-10919851-B2 2-pyrrolidine phenylhydrazides antibacterial agents ABAC Therapeutics, S.L. (ES) 2021-02-16 US disclosed
EP-3490984-B1 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS Abac Therapeutics Sl (ES) 2020-09-09 EP disclosed
US-20190177272-A1 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS ABAC Therapeutics, S.L. (ES) 2019-06-13 US disclosed
EP-3490984-A1 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS Abac Therapeutics, S.L (ES) 2019-06-05 EP disclosed
WO-2018020004-A1 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS ABAC THERAPEUTICS, S.L (ES) 2018-02-01 WO disclosed
CN-106589997-A Flame-retardant wood-plastic common-squeezing material and preparation method thereof 黄山贝诺科技有限公司 2017-04-26 CN disclosed
US-9266880-B2 Substituted azaindazole compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2016-02-23 US disclosed
EP-0562575-A2 N-substituted-3-(substited hydrazino)-benzenesulfonamide derivatives, prepation process thereof, and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-09-29 EP disclosed
EP-0384602-B1 N-substituted-3-[(2,3-dimethylmaleimido) amino]-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-08-04 EP disclosed
US-5198566-A N-substituted-3-(substituted hydrazino)-benzenesulfonamides KUREHA KAGAKU KOGYO K.K. (JP) 1993-03-30 US disclosed
US-5151114-A Applying to weeds ARAHORI HIDEO (JP) 1992-09-29 US disclosed
US-5129942-A For controlling monocotyledonous and dicotyledonous weeds on agricultural land KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-14 US disclosed
US-5059238-A Controlling mono- and dicotyledons KUREHA KAGAKU KOGYO K.K. (JP) 1991-10-22 US disclosed
US-5028255-A N-substituted-3-[(2,3-dimethylmaleimido)amino)]-benzenesulfonamide derivatives, hebicidal compositions and method of use KUREHA KAGAKU KOGYO K.K. (JP) 1991-07-02 US disclosed
EP-0382437-A1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177272-A1 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS ATAD2, ATAD2B, ATAD5 CA2 1951/4885CA1 4843/4885CA12 4490/4885
US-10919851-B2 2-pyrrolidine phenylhydrazides antibacterial agents ATAD2, ATAD2B, ATAD5 CA2 1951/4885CA1 4843/4885CA12 4490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.