SCHEMBL9612906

SCHEMBL9612906

Cc1cccnc1-c1cccc(-c2c3ccccc3c(-c3cccc4c(C5CCCCC5)cccc34)c3ccccc23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.36
CNR2 P34972 1/20 0.34
PTPN5 P54829 3/20 0.34
PTPN2 P17706 1/20 0.34
PDK2 Q15119 4/20 0.34
PDK4 Q16654 3/20 0.34
HRH3 Q9Y5N1 1/20 0.34
PDK1 Q15118 1/20 0.34
PDK3 Q15120 1/20 0.34
HTR1A P08908 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
PTGS2 P35354 1/20 0.33
ABL1 P00519 1/20 0.33
CAMKK1 Q8N5S9 3/20 0.33
CAMKK2 Q96RR4 3/20 0.33
GRIA2 P42262 1/20 0.32
PDE10A Q9Y233 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR5 Q9H228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9613135 0.84 PTPN5 (0.36) PTPN5PTPN2PDK2HRH3CAMKK1
SCHEMBL9612909 0.83 CYP2A6 (0.45) CYP2A6CNR2PTGS2ABL1GRIA2
SCHEMBL9613123 0.82 CAMKK1 (0.34) PTPN5PTPN2HRH3CAMKK1CAMKK2
SCHEMBL9612987 0.81 CYP2A6 (0.44) CYP2A6PTGS2
SCHEMBL9612907 0.81 CYP2A6 (0.43) CYP2A6
SCHEMBL18174566 0.80 CYP2A6 (0.53) CYP2A6CNR2PDK2ABL1GRIA2
SCHEMBL21565051 0.79 PTGS2 (0.43) CYP2A6CNR2HTR1ASLC6A2SLC6A4
SCHEMBL9612978 0.78 PTGS2 (0.41) PDK2PDK4PTGS2ABL1CAMKK1
SCHEMBL9612985 0.76 COMT (0.45) CYP2A6CNR2PTGS2GRIA2
SCHEMBL5667889 0.74 CYP2A6 (0.46) CYP2A6CNR2PDK2PDK4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed