SCHEMBL9612985

SCHEMBL9612985

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4cccc(-c5ncccc5C)c4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.45
CYP2A6 P11509 1/20 0.41
TRPV1 Q8NER1 3/20 0.40
CKS1B P61024 3/20 0.39
SKP2 Q13309 3/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP2C9 P11712 1/20 0.38
CNR2 P34972 1/20 0.36
SQOR Q9Y6N5 2/20 0.35
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
SYK P43405 2/20 0.34
AURKB Q96GD4 1/20 0.34
INCENP Q9NQS7 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612987 0.91 CYP2A6 (0.44) CYP2A6CKS1BSKP2ALDH1A1SQOR
SCHEMBL9612909 0.87 CYP2A6 (0.45) CYP2A6TRPV1CNR2SQORCYP1A2
SCHEMBL18174566 0.87 CYP2A6 (0.53) CYP2A6TRPV1CNR2NPC1GRIA2
SCHEMBL9612907 0.85 CYP2A6 (0.43) CYP2A6ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL9613001 0.84 COMT (0.46) COMTCKS1BSKP2ALDH1A1CYP2C19
SCHEMBL18272696 0.82 CYP2A6 (0.41) COMTCYP2A6TRPV1CKS1BSKP2
SCHEMBL18174586 0.81 CYP2A6 (0.44) CYP2A6TRPV1CNR2GRIA2EPHX2
SCHEMBL9612842 0.81 PTGS2 (0.50) COMTCKS1BSKP2ALDH1A1CYP2C19
SCHEMBL18174725 0.81 CYP2A6 (0.49) CYP2A6CNR2SQORCYP1A2MAPK1
SCHEMBL15161094 0.81 CYP2A6 (0.49) CYP2A6CYP1A2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed