Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 8/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612848 | 0.81 | DHODH (0.41) | PTGS2DHODHPDK2PDK4ABL1 | |
| SCHEMBL16189088 | 0.79 | MKNK1 (0.54) | PTGS2DHODHMKNK1MKNK2PRMT5 | |
| SCHEMBL9612930 | 0.79 | DHODH (0.50) | DHODHMKNK1MKNK2 | |
| SCHEMBL9612955 | 0.79 | DHODH (0.47) | PTGS2DHODHMKNK1MKNK2PRMT5 | |
| SCHEMBL9612969 | 0.79 | DHODH (0.47) | PTGS2DHODHMKNK1MKNK2PRMT5 | |
| SCHEMBL9612906 | 0.78 | CYP2A6 (0.36) | PTGS2CAMKK1CAMKK2PDK2PDK4 | |
| SCHEMBL18174795 | 0.77 | DHODH (0.46) | DHODHMKNK1MKNK2 | |
| SCHEMBL18174786 | 0.75 | DHODH (0.47) | PTGS2DHODHMKNK1MKNK2PDK2 | |
| SCHEMBL9612965 | 0.75 | PDK2 (0.37) | PTGS2CAMKK1CAMKK2PDK2PDK4 | |
| SCHEMBL9613123 | 0.75 | CAMKK1 (0.34) | FEN1ALOX5APCAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012070535-A1 | ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | JNC株式会社 (JP) | 2012-05-31 | — | — | WO | disclosed |