SCHEMBL9612931

SCHEMBL9612931

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cc2)cn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.42
PDK2 Q15119 1/20 0.42
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
MAPK10 P53779 2/20 0.39
JUN P05412 1/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
PKM P14618 1/20 0.38
CA12 O43570 4/20 0.37
CA9 Q16790 4/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
USP1 O94782 1/20 0.37
WDR48 Q8TAF3 1/20 0.37
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23555400 0.88 ENPP1 (0.51) PDK2ENPP3ENPP1MAPK10JUN
SCHEMBL18174772 0.86 PDK2 (0.42) PDK2MAPK10JUNRAB9ANPC1
SCHEMBL17532877 0.86 NPC1 (0.44) PDK2RAB9ANPC1PKMUSP1
SCHEMBL9429745 0.84 ENPP3 (0.50) DHFRPDK2ENPP3ENPP1MAPK10
SCHEMBL17532886 0.83 CYP11B1 (0.40) PDK2MAPK10JUNRAB9ANPC1
SCHEMBL16814673 0.82 CA12 (0.49) DHFRENPP3ENPP1RAB9ACA12
SCHEMBL29751906 0.82 CA12 (0.49) DHFRENPP3ENPP1RAB9ACA12
SCHEMBL9612932 0.81 ALDH1A1 (0.55) RAB9ANPC1KDM4EMAPTALDH1A1
SCHEMBL10032758 0.81 CYP11B1 (0.45) DHFRRAB9ANPC1PKMKDM4E
SCHEMBL16189031 0.80 PSD (0.39) PDK2RAB9ANPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed