Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613686 | 0.79 | KDM1A (0.47) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL9613683 | 0.78 | KDM1A (0.44) | F10PRSS1PRSS2PRSS3OPRK1 | |
| SCHEMBL12188599 | 0.77 | OPRK1 (0.53) | KMT2AMEN1OPRK1PARP10PARP14 | |
| SCHEMBL7071501 | 0.77 | CA12 (0.67) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL11937397 | 0.77 | F10 (0.64) | F10PRSS1PRSS2PRSS3OPRK1 | |
| SCHEMBL12188618 | 0.76 | OPRK1 (0.58) | KMT2AMEN1GAAOPRK1PARP10 | |
| SCHEMBL12099943 | 0.75 | OPRK1 (0.60) | KMT2AMEN1GAAOPRK1PARP10 | |
| SCHEMBL14597201 | 0.75 | ACHE (0.61) | KMT2AMEN1 | |
| SCHEMBL13846190 | 0.75 | KMT2A (0.57) | KMT2AMEN1GAAOPRK1PARP10 | |
| SCHEMBL8357204 | 0.74 | EPHX2 (0.61) | KMT2AMEN1GAAOPRK1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071469-A2 | HISTONE DEMETHYLASE INHIBITORS AND USES THEREOF FOR TREATMENT O F CANCER | NEVADA CANCER INSTITUTE (US) | 2012-05-31 | — | — | WO | disclosed |