Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556947 | 0.82 | GRIN2D (0.62) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7476480 | 0.81 | ADORA3 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL10487991 | 0.73 | ALDH1A1 (0.46) | GRIN1GRIN2BALDH1A1PPARGSMN1; SMN2 | |
| SCHEMBL7484219 | 0.73 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7477922 | 0.72 | ADORA3 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7486654 | 0.71 | CYP1A2 (0.49) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL7488589 | 0.71 | ADORA3 (0.44) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL9093498 | 0.71 | ALDH1A1 (0.56) | ALDH1A1APOBEC3AAPOBEC3GGSRMEN1 | |
| SCHEMBL7811625 | 0.71 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8191455 | 0.71 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166155-A | Neurological or psychiatric diseases | NOVO NORDISK A/S (DK) | 1992-11-24 | — | — | US | disclosed |