Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.47 |
| ▸ | MMP1 | P03956 | 6/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.47 |
| ▸ | MMP3 | P08254 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 6/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614196 | 0.92 | MMP2 (0.49) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL9614215 | 0.90 | MMP2 (0.60) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10419552 | 0.89 | TRPA1 (0.48) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10420693 | 0.89 | TRPA1 (0.48) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10420420 | 0.89 | TRPA1 (0.48) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10420884 | 0.88 | MMP2 (0.54) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10420440 | 0.88 | MMP2 (0.54) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10419465 | 0.88 | MMP2 (0.54) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL10420695 | 0.87 | MMP2 (0.55) | MMP2MMP1PDE4APDE4BPDE4C | |
| SCHEMBL9614061 | 0.86 | ALDH1A1 (0.50) | MMP2MMP1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |